Does being hairless make it easier to digest, yes I strongly believe it does. Do I think it normally makes a difference? No. Most healthy snakes have no problem being fed animals with hair, the times I feel like it can make enough of a difference to matter would be with animals who have been sick or regurging, or babies that come from weak lines that are known to have regurge problems I feel like it's best to keep them on hairless stuff for a longer time growing up....hypo brb's would be an example if they haven't been outcrossed enough.