Hmmm... First off, I'm sorry I had an aggressive corn (not the same as a ball, but still) who struck ALL THE TIME. A method a corn breeder told me about really worked for us. I wonder if it would work for you...
Although, I don't have any experience with fiesty ball pythons, and if someone thinks this is a downright bad idea, please chime in!

This is what I was advised to do for my yearling corn snake (about half the weight of your ball python):

Take her out every day for 1-2 *hours* at a time. If she struck, I was advised to follow through with my motions anyways, and not to pull back (as natural as it is to do that). Basically to just put up with the biting and striking. Personally I got used to it, so gloves were not needed.
I was told to just sit with her. Just let her do her thing, but get her to stay with me - so no letting her go off of your body. Even just watch TV or a movie with her, but just keep her out.
I was told to only put her back once she was calm and relaxed (or stopped freaking out, if that's all she did the whole time she was out). If she went crazy, I was advised to disregard this. I don't mean ignore her or make her more upset, but just let her do her thing and try not to react to her. Even if I covered her with dark clothing or whatever to calm her down, as long as she's on me or with me somehow.

So, after 6 days of this, she was a completely changed snake! I sh*t you not. She had already been with me 3 weeks, and her temperatures were accurate and she was eating regularly (3 weeks in a row) before I tried this. I tried not touching her for a long while, and all that. Didn't seem to work. But this method did.
My corn used to strike at me CONSTANTLY, in and out of her vive. I can't even tell you how many times she tagged me. I'd say easily 10-20 times in one attempt at getting her out of her vive.
But now, she hasn't struck at me since I tried this method. She's FANTASTIC.


So... I'm not sure how others will feel about this. Maybe it's too much, or it would be too stressful for a ball python. I really don't know, so please take this with "a grain of salt".
If anyone has done something like with a BP this it might be more helpful.