Many people will say they breed again right away (as soon as she'll take the male). If the male is left with her at birth, she could get pregnant immediately and be carrying while nursing the last litter.
I *personally* like to give my females little breaks in between litters. I usually wait 2-3 months in between litters, approximately 2 months from weaning one litter before the next is born. I'm experimenting a little since I haven't bred feeders before (I did breed pets, but that was different and I had the luxury of giving my rats long breaks, if they were ever even bred more than once!), but so far this seems to be working for me, and my females are staying in good condition, without getting too thin or too fat in between litters.








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