Yeah that is a little bizarre but not unheard of. I have a lot of snakes so I never have all of them go off feed at once, but I've definitely had a large chunk of my collection stop eating for no apparent reason.
I would give a substrate change a try and then leave them alone for a full week or two (for good measure). Pre-scent the room hardcore before feeding to get them ready and see how it goes!
If you have the space, you could also try moving some to bigger tubs or smaller tubs to see if the change in scenery kick starts anything.
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