It's actually happened to me several times. My room is typically around the high 70's to low 80's (degrees farenheit), rarely dropping below the mid 70's One was a subadult female hypo who ate a small rat, the GFI on the outlet had been tripped. Another time was an adult male albino who also ate a small rat. The Ranco thermostat had stopped working. (I've actually lost a few other snakes due to ranco thermostats that quit working, which is why I'll never buy another ranco thermostat) Both snakes meals were pretty typical for them and they had eaten meals that size before with no problems. Other snakes in the rack did not appear to have any problems digesting their meals. I'm not sure why some snakes would die and the rest were fine, but the only thing I was able to find that was different then usual was that the heat had been off.