It may matter when breeding a much larger species to a ball. Kind of like with Ligers and Tigons. Ligers carry maternally-inherited genes from the tiger that cause an adult size that can be larger than the tiger itself. Tigons have lioness mothers and are much smaller. The same is seen in some large breeds of dogs.

That is all mammals of course. There is limited information on ball python hybrids and the only concrete answers would be from people who have tried your theory first hand.