Forgive me if i'm not understanding this, are you saying the advantage of 5-6 smaller meals is that people tend to overeat when eating less frequently and overall caloric intake is higher for those eating less often?
Yes, largely due to the crappy food available these days. By smaller I don't mean portions.

That said, if macros are tracked effectively then there will be no advantage.
perhaps, but I find it hard to get the right amount of protein from just 2 or 3 meals to build lean body mass since the body cannot store protein.

yes, its safe to assume the average American ingests enough fat but one of the first things people eliminate when eating "healthy" is sat fats or even fats in general
right, but there is a big difference between an order of deep fried onion rings and a handful of cashews.

As far as GL, GI, and their effect on insulin are concerned insulin's role as a fat storage hormone is far overblown and can't overcome a caloric deficit.
http://articles.elitefts.com/trainin...claims-part-1/
I stated that merely as trivial info, agree to disagree. as do most of the people commenting on the article.