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    Re: Calico's - Any lethal combos to stay away from?

    Quote Originally Posted by Toolarmy1 View Post
    ^^^^ Uh....

    Um, okay. Perhaps it's accepted by YOU that this makes sense, but it does not. It's been proven by countless breeders, (even in Kevin's Lethal Combos video he references it) that a dominant gene does not HAVE a homozygous form. That is the whole point of them being dominant. If there was the possibility of a homozygous form, it would be a co-dominant gene. Breeding a spider to a spider is not lethal. It might not be SMART due to the spider gene's dingy nature (although the rumour of getting super wobbley spiders from breeding two together has been dispelled as well). Of course there are times when things go wrong, it's nature. The super champagne that was hatched and did not survive, that does not mean that dominant genes can have a homozygous form. It means in that one instance, something went wrong on a genetic level and caused an anomaly. If someone were to breed two calicos together, they'd just get a good majority of calico offspring. Same with spiders and pinstripes. I've bred pinstripe combo males to pinstripe females more than once and have never seen an issue come of it.
    Heh, Dominate just signifies that it only takes one gene to express it. All known traits have two copies of the gene, one from mom, one from dad. There are polygenic traits that are sometimes controlled by more than 2 copies (Tiger gene in moreliea spilotes comes to mind). But just because a gene is dominate does not mean it does NOT have to have a homozygos form. It just means that the homozygos form is not phenotypically different. But IS genetically different, where the homozygous offspring of the dominate trait will ONLY produce the trait from any and every breeding because it only has that gene to give.

    End very basic genetics rant.
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