Calico's - Any lethal combos to stay away from?

[Toolarmy1]

as far as calico combined with other genes, there is nothing lethal (as far as i know). calico x calico is another issue. same with spider x spider or pinstripe x pinstripe. with no known homozygous form it is accepted that the super form is lethal. since a super form never shows up and they have to have an allele from each parent, the only logical conclusion is it's lethal.

^^^^ Uh....

Um, okay. Perhaps it's accepted by YOU that this makes sense, but it does not. It's been proven by countless breeders, (even in Kevin's Lethal Combos video he references it) that a dominant gene does not HAVE a homozygous form. That is the whole point of them being dominant. If there was the possibility of a homozygous form, it would be a co-dominant gene. Breeding a spider to a spider is not lethal. It might not be SMART due to the spider gene's dingy nature (although the rumour of getting super wobbley spiders from breeding two together has been dispelled as well). Of course there are times when things go wrong, it's nature. The super champagne that was hatched and did not survive, that does not mean that dominant genes can have a homozygous form. It means in that one instance, something went wrong on a genetic level and caused an anomaly. If someone were to breed two calicos together, they'd just get a good majority of calico offspring. Same with spiders and pinstripes. I've bred pinstripe combo males to pinstripe females more than once and have never seen an issue come of it.