You might worry about hair kicking more than a bite. I wouldn't recommend handling a GBB.
Their venom isn't really bad but its still venom. Pain and itching and fangs are going to hurt no matter what.
You would also have to worry about the spider hitting the floor. They are more flight than fight.
My thumbs are ate up right now from my LPs. Even when they don't "kick", it can still get you during cage care.