My vet suggested that instead of directly spraying products like Reptile Relief, Mite Off, etc.on the snake, spray a white paper towel and use that to wipe down the snake. It's less stressful to the animal as you're not chasing it around the enclosure with the spray, you end up using much less of the product so you save money, it's easier to apply the product to the vent and the cleft under the snake's chin where mites love to hide, and you can check the paper towel easily for mites.