I've seen retics that aren't very fast strikers, but most generally are I'd say. Definitely don't want to use your hands on a large one.
Doesn't matter if they are or are not, just like many other animals they will go into breeding mode.
Many tend to be aggressive, but there are ones that mellow out. People usually import for a new bloodline or for one that looks different than the others in hopes of being a new morph. And no matter if it's wild caught or CB make sure you have more than one person with you in the room when dealing with a large snake, retics have great feeding responses and if a large one latches onto your hand you won't be able to get it off alone. I know of some retic owners who keeps knives or guns in the pocket in case worse comes to worse but that would be the last option.
I don't own any retics but I've looked into them for a couple years now haha.