Well....I hold Pajamas once every couple of weeks...he's getting too big to really 'HOLD' though..so I let him roam the bedroom, stretch out, maybe soak a little, and I clean his cage. I pet him every day though, and we have a fun game when he's awake...(When I walk past his cage, he'll go up to the plastic and flick his tongue at me, so we do this for about 5 minutes...yeah. he's odd.)
Once Tika, my Indonesian Tree Boa gets settled, I'll likely hold her quite a bit...she loves to just wrap around your wrist and sit =3
And apparently, my new retic, Zazzles, is feisty, so I'll be holding her daily when she settles in so that she's easier to handle when older.
(jammers and zazzles are both retics.)