Mites. Dang.

[Anatopism]

To the OP:
Buy a bottle of PAM (Provent-A-Mite, not cooking spray ), follow the directions exactly. Do NOT put PAM directly on an animal, and allow the surface to dry 1-2 hours after spraying before allowing an animal to come into contact with it. Most people do not take their water dishes out of the tubs when treating for mites - I do, it is a personal preference, that I use to limit the chance of passing the chemical into water and being ingested.

You can also pick up some 'Natural Chemistry - Reptile Relief' spray, and this is safe to put directly on the animal. Do not use during shed, and avoid the face/eyes/heat pits. This will kill any live mites currently on the animal.

PAM - effective both on live mites, and acts as a long term preventative for any that may hatch out later
Natural Chemistry mite spray - Is not preventative, only kills mites currently active and not in egg form, but can be used directly on the animal.

sounds very bad. sounds really like some nasty mites. If they like to be under the scales of snakes, they are bloodsuckers.

You need to visit a vet ASAP. I guess it will be a medication that is (more or less) harmless for the python but deadly for the mites, or the whole surface of the snake gets treated with something. And at the same time all substrate and everything needs to be replaced or cleaned to the point of being sterile. Good luck! But this time, i think, this forum cannot replace a veterinarian. Consider anything i said merely as hints, except that you really need a professional now.

Kurtilein, while I certainly appreciate your desire to help, please take a moment to take a step back, and not provide definite advice that you have no experience with. I can tell you're not stupid by your other posts, but perhaps a little too eager. Being overly helpful and regurgitating information you've stumbled across but do not truly know, can be just as useless or harmful as incorrect advice.

"Provent a mite. Follow the directions. The ones not on the snakes will either go back to the snakes or die. And the ones that go back to the snakes will get killed off by another treatment of provent a mite."

That might work. But i would still maybe cautiously advise to see a vet. Preferrably one with snake and/or reptile experience. Thats the safe way.

Best Regards

No. Evidence of your inexperience with snakes, reptiles in general, and the reptile hobby as a whole. I don't mean to be offensive, I'm just pointing out the instability of your advice.