Like Marissa I'm a horse person, and I have two idiot Scottie dogs so I'm definitely not a germaphobe. But I am very leery of transferring germs to or between snakes (also want to remove mammal smells from my hands) so I wash before and after. And if I have one in quarantine, I spray my hands with F10 (bad I know) first and then wash them. Horrible on the skin, but better than taking my entire collection to the vet.