In my personal opinion I don't agree that making hybrids qualifies as unethical. If it does and the reasoning for it's "unethical-ness" is not keeping good blood lines in captivity then ALL back breeding/line breeding/inbreeding/close breeding and morph breeding should also be deemed unethical.
Just trying to follow the logic, as I stated previously, I don't agree that producing hybrids is unethical or that doing so would damage your reputation.
Now after that little disclaimer, I looked into the chromosome numbers of both Boa constrictor and Epicrates cenchria both have 36 chromosomes. The number of chromosomes does not necessarily need to match up for you to get offspring, however, if you do get offspring the hybrids have a good chance of being fertile.
I don't personally know of any rainbow boa, boa constrictor hybrids.