Usually, what I do when I go out of town for a few days is, I will feed them about 4 days before I leave. That gives them time to digest, and if any poop, I can clean it up before I leave, and on the off chance that one of them regurgitates, I can clean that up as well. A regurgitated rat is not something that you want laying around for a week. As for water, I just put in an extra bowl of water for each snake. If I am going to be gone longer than a week, then I will have a friend come over and check on them and change water. If you choose to have someone check on them, make sure that you show them exactly how to open, close, and secure the cage. You don't want to come home and find that your snake has escaped because the cage wasn't properly closed.
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