I am focusing mostly on down syndrome sites, since its about the only thing that seems to have anything close to the data i'm looking for. down syndrome is cause by having an extra chromosome 21. While there seems to be very conflicting numbers, many of them say, that if the parent has down syndrome, you basically have a 50% chance of passing it and if both parents have it, the chances are even higher (75% would make sense). what I still fail to find is why that 2nd extra chromosome doesn't get passed. I keep reading basically that it doesn't just don't know why.