This is where I have a problem with people recommending NIX. From all of the NIX vs PAM threads I've read, everyone claims that the NIX is essentially the same thing as PAM. But it says on the can of PAM that it is NOT to be used on the animal. I would think that spraying your snake with NIX would introduce the same chemicals as PAM to the snake, potentially causing the same problems. There are no instructions on a bottle of NIX to tell you how to use it to treat a case of snake mites, so you're going on an assumption and putting your snakes at risk over something that's never been tested safe to use on live reptiles. PAM has been tested and it's fully documented how to properly use it to eradicate a mite infestation. I had mites from my first (PetCo) snake. I came here, got the advice of PAM, ordered a can and treated according to the instructions. One treatment was all I ever needed, and the extra few bucks for PAM was worth the peace of mind.