Some good pointers I got here when I first started talking of what to breed to what, are what I will recommend to you...
Breed what YOU like. If you like LesserBee's then breed for that. You can't go wrong with throwing a Lesser at most common morphs anyways. I personally will be putting my 0.1 Spider with my 1.0 Lesser in a few months.... Lesserbee's are high on MY list. I will breed what I like because you will not always be able to sell what is going for a buck at the moment, so you might end up "owning" them for a while.
My ultimate goal is to breed for Nuclear Spiders and Nuclear Pinstripes next year. I got a FireButter this past year for that project next year... note how I have 4 Spider/Pinstripe/Spinner girls to pair with the FireButter next fall.
The odds gods must surely be against me if I can't hit a Nuclear next fall.