interesting concept, although im not sure the snake will remember the last time you held it. I am sure however they sense fear.
Sensing fear could be a few things, Endorphin's your body sends out or different heat patterns in your body
My normal is cool with everyone
My Lesser on the other hand knows my wife doesn't care for him and he senses that i'm sure of it.. He will come out of his hide when she is in the basement but retreats back to it when she leaves