She is probably hungry! A single adult mouse isn't really enough for an adult ball python. I woud bump her up to two mice a week or a small rat. I don't know why someone didn't notice this a couple months ago when you first posted.

Also, feed in the home enclosure. You just set yourself up to get bit if you feed in a separate container. Your snake will not become more aggressive if you feed in the home enclosure, contrary to popular belief.