One eye lacks pigment, one does not. This is actually not too strange, if you consider how the piebald patterning works.
The pigment in the eye with the black pupil is strong enough to make it dark inside the eye, so the pupil appears black. In the other eye, there isn't enough pigment to block light passing through in areas it shouldn't, so light reflects back out off of the retina, and it looks red from the blood vessels in there.
I would be curious whether the snake is blind in that eye.
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