Right, a large number of adult normal females can save your butt. Don't put all of your eggs in one basket, so to speak! You'll want at least 2 good quality co-dom males, and a lot of normal adult females--that will give you a quick return.

If you CAN, get all of your animals from a single source, and avoid quarantine issues.

Quarantine is massively important, and cannot be understated. Plan for it. Plan to quarantine for 12 months. Yes, everyone's saying 3, but 3 is a token quarantine period, not a serious one. The big bad diseases that can kill all of your animals can and do incubate for longer than 3 months. Some have been tracked to incubate for as long as 10 months. Be safe.

Once you have your initial animals, when you do your buying each year, keep them and their rack separate from your existing animals. Remember to quarantine a rack from the arrival date of the LAST animal that went into it. You will probably want 2 quarantine areas, so you can begin the next year's buying before the previous year is out of quarantine. Remember that it's better to be 'too cautious', because 'not cautious enough' could result in the loss of everything. The larger your collection grows, the more you have to lose.

Anyone who's been on the forums for a couple of years has heard the horror stories of what can happen when quarantine isn't strict enough. Businesses have been destroyed, and lives devastated.