Just to show some numbers on this that I have produced myself. I have bred Spider to Spider 25 times in total, the last time was 4 years ago. Out of all of them I had 1 slug and 3 eggs go bad during incubation. I did use ultra sound and every number is the exact same for follicle count vs eggs/slugs. I was very lucky and hatched 5 males the first year and they were breeding normal females the next year and were not homo spiders. The females that were raised up that were spider and bred to normal males produced the standard outcome. This year is the last year I will be doing these breedings and currently have 91 eggs incubating from those pairings. So we will see. But so far nothing at all has shown any form of lethality or a super form at all. So with the amount of breedings done on this is a decent amount for a base case study and more can be done to add to it. As a side note there were no multi gene animals used through the entire process it was only spider to spider and then offspring to normals.