Well I keep a spare tub or two on hand and then I put the kids in there on papertowels. I then dump out the old tub (if you are using bedding) and then wipe it down with a clorex wipe and then refill. I run the water dishes and hide boxes in the dish washer. I completely clean out my tub every couple of months (the ones with bedding). The snakes that are on paper get cleaned ALL the time. If "dinner" poops on it, if they spill their water, or if they poop I clean tub and change the paper.
I hope this helps!!
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