I have 2 cases of ri right now my mojave that is pretty bad hes on bytril and f-10 and a normal that isn't so bad is just on f-10. Its been a week for mojave on bytril plus f-10 and i think hes doing ok he still has all the signs of an ri but hes not getting worse. And the normal that is just on f-10 has gotten worse. So im not so sold on just f-10 working just yet but the normal has only been on this treatment for three days now im going to give it four more days to make it a week then bring her to the vet if it doesnt show signs of getting better. Both of them are eating also so i think thats a good sign. I think the product is safe but effective i cant say...