I own a female Biak green tree python. She was very aggressive when I first got her, but after handling her 2-3 times a week she settled down a lot. Although some green tree pythons are puppy dog friendly I wouldn't recommend handling them too often especially as neonates, their spines and tails are extremely delicate and can easily be injured.

Also never attempt to handle one during the night, they will mistake your hand for a nice meal. (learned from experience lol)