You might stress your snakes out (can very much impact their immune system).
You might experience male-male combat.
You might experience mating if male-female.
You might experience dominance behaviors.
Feeding can be tricky, especially with food-active snakes such as carpets and bredlis.
I provide different husbandry for various types of carpet pythons (including bredlis).
If you housed two females together, would there be a chance that they would live for a decade or two and be healthy? Sure, but there are risks.
At the very least, a 4x2x2 is not large enough for two adults to live in all year long. It's suitable for a lone adult, or a pair only when introduced for mating.