Always in the enclosure. I can't imagine dragging out my 5 foot girl while there's rodent scent around...It's just much safer, easier, and less stressful in cage. It really would be a nightmare to try and move around bigger boas when they're in feeding mode.
I don't hook train myself, because Eve is very docile. She always acts like she's going to strike when I reach in to handle her or clean, but as soon as I actually touch her, she calms down completely.