I would just use one heat pack...They are better off a little cooler than too hot.
Another thing to check when making this decision is the weather in Nashville, Tenn...That's where all the packages go to be sorted.
http://www.weather.com/weather/tenday/USTN0325
Also when the weather is cool at night, but warm during the day I call FedEx to check the recipients zip code and make sure they are in a 10:30 am delivery zone...Some delivery zones are 12n and even 4pm! You would want to have the later shipments held at the FedEx hub.