No gender difference that I have noticed. I have one male that's puppy dog tame, and one female that's puppy dog tame. One female that would probably rather I don't ever touch her, and one male that you have to watch real careful when he is in feed mode. One male that I think may be bi-polar, because sometimes he is a doll, sometimes he is like grease lighting and just wants back in his tub. Then there's my new girl, who I think is going to be another puppy dog.