If you feed them a good diet, keep them with fresh water and clean cages, you shouldn't have issues.

If he's having tons of issues, he should probably look at what he's doing wrong. I rarely have babies eaten, never have had lice, and once I got the routine down, I can fill all the water bottles in about five minutes or so, and clean all the bins in about an hour(about 20 various bins/bottles).

You do need to think ahead to what you'll do with all the used bedding, and make sure there's good ventilation in the area you keep them. Racks make everything so much easier, and have a few extra bins(easier for cleaning and for replacements if rats chew them).

Newbie mistakes to me... don't mess with the babies too much, let the moms care for them. Feed good food, and don't let them run out of water. Don't keep biters, chewers or troublemaker rats. Don't forget to figure in space to raise replacement breeders and your feeders.