Well, I don't feed F/T because we once had two snakes in at the vet with what we eventually found was internal gangrene because the rats weren't thawed properly.
I feed live and not pre killed because, well, I've never had a problem with it. While I'd have long stints of fasting when I fed pre killed, I found my snakes became more aggressive feeders and all around better eaters for live.
I've only had one rat show a tooth to my big gal, Sienna, and I reached in and snatched him up before the situation could progress. I got a good bite out of it, but that's the only issue I've ever had. It seems underwhelming in lieu of the benefits I've noted. (: