For the most part the morphs are exactly like their normal counterparts, but there are a few morphs that have issues.
You mentioned the bumble bee. To produce a bumble bee you breed a pastel with a spider ball python. The spider morph has what is called a "wobble" this is a neurological issue that causes them to lose motor control, and seem to not be fully aware of their orientation. That being said it is rare for the wobble to cause any issues and I personally feel that people make way to big a deal of it. Some have it worse than others. I have one and 99% of the time you wouldn't even know that he had any issues.