Has anything in the environment outside of the cage changed or become stressful? I know it sounds crazy, but when we have friends with kids over, or when my hubby and I fight () my BP gets stressed, even if nobody is even looking in her direction that day/night. She's never hissed or struck, but she's much more tense and hides deeper inside her hide than normal. Same thing when we're doing home repair--anything that will cause good reverberations through the structure of the house (stomping, slamming doors, even vacuums sometimes) will cause her to act differently than under normal circumstances. Her normal behavior is to just hang out in her hide. At night she'll poke her head out almost all the time--hungry or not.
As far as humidity, mine HATES it when I mist. It really got in the way of our relationship. I stopped misting and started using a humid hide. I dampen a wad of moss and keep it in her hide. I also keep dampened moss that I situate on a piece of decorative driftwood, and make sure the water bowl is large enough and situated under the lamp. She's never had a bad shed doing this, and it definitely doesn't stress her out nearly as much as misting.