Satiety has been studied extensively in mammals, birds and fish but very little information exists on reptiles.
Here we investigate time-dependent satiation in two species of constricting snakes, ball pythons (Python
regius) and yellow anacondas (Eunectes notaeus). Satiation was shown to depend on both fasting time and prey
size. In the ball pythons fed with mice of a relative prey mass RPM (mass of the prey/mass of the snakeŚ100)
of 15%, we observed a satiety response that developed between 6 and 12 h after feeding, but after 24 h pythons
regained their appetite. With an RPM of 10% the pythons kept eating throughout the experiment. The
anacondas showed a non-significant tendency for satiety to develop between 6 and 12 h after ingesting a prey
of 20% RPM. Unlike pythons, anacondas remained satiated after 24 h. Handling time (from strike until prey
swallowed) increased with RPM. We also found a significant decrease in handling time between the first and
the second prey and a positive correlation between handling time and the mass of the snake.