Well considering the frosts of 2010 killed of alot of these invasive monsyer killer snakes we keep hearing about i think its safe to say they are not going to survive even in the keys not to mention north of the keys. The only state in the country pythons would be able to survive long term i would say is hawaii but considering how tight there reptile laws have been on the islands thats not gonna happen. So i think we have a better chance of being killed by zombies then pythons lol