I do NOT believe that handling is stressful for a snake that has good husbandry and was frequently and gently handled while young. Look at the body language of your snake. If it ball up or assumes a strike position and freezes in terror when you take it out, then it is stressed. If is leisurely explores, it's fine.

I will often hold my snake while I watch TV, and I will ruffle a blanket so that she can crawl through the folds, so she still has a secure feeling while exploring. She has NEVER balled up on me, nor she has she ever been aggressive, so she is either exceptionally brave or exceptionally well adjusted.

The point is, your snake should never be out of its home for HOURS, but if you have gently and patiently "socialized" it, then short handling sessions shouldn't bother it at all. The great thing about ball pythons is they have a very clear way to communicate that they are stressed or fearful that gives them their name. Your snake shouldn't fear you unnecessarily. It should view you as neutral: not edible, but not threatening, therefore largely uninteresting.