Hi Emily,

In general, with ball pythons if you have to choose between ideal temperatures or ideal humidity - always go with maintaining ideal temperatures. You can always assist with an adhered shed by soaking or otherwise providing moisture if your low humidity causes shedding problems. On the other hand, humid, too-cold temps can lead to respiratory (and other) illness - a much worse fate.

Ball pythons are pretty tough, long-lived critters if you can provide the basics for them. And good temperatures are at the top of the list of basics for keeping them healthy.