The house we lived in last year in Colorado was infested with mice when we moved in. It didn't seem to phase my snakes at all, though. I made sure when the exterminator came out that he knew I had snakes and exactly where they were so that he wouldn't spray any poisons anywhere near them. We used poison traps on the mice, so it wasn't anything the snakes were going to get into anyhow.
No matter how tempting it might seem to be, NEVER give a wild-caught mouse to your snakes. No telling what kinds of parasites it might be carrying, nor what kinds of toxins it might have ingested. Besides traditional rodent poisons that you or others might have put out, they also get into household chemicals. Under my kitchen sink in that Colorado house, they chewed through part of a box of Cascade and ate some of that powder. Ick!
We were in that house for a year, and never did totally solve the mouse problem, although the amount of activity was cut down quite a bit. Pain in the tush, for sure. But the snakes were unaffected.![]()