Doesnt sound like you have done much research on ball pythons. But I feed mine once a week but babies i want to get to breeding size quick(mostly new males) I feed twice a week. You dont have to handle them everyday either. And If they are hatchling i guess you could keep them in a 10 gal as long as it has proper heat, humidity, and hides and a water bowl. I Like rack systems better than aquariums though. If they are adults 10 gal wont be enough for 2 adults. How much do they weigh and how old are they?