Nothing frozen will ever compare to a fresh meal. PERIOD. It is well-known that freezing kills thiamin (Vitamin B) and freezer burn damages tissue. if frozen too quickly moisture crystallizes damaging the tissue, however it would take a lifetime of sub-par meals and freezer burnt prey to "cause diseases" though, i thinks thats a little overboard.

On that note, have a kid and decide to feed it only frozen food its whole life. My bet is a noticeable difference between your childs health and its peers!

IMHO