Transporting a Ball Python in the car is a relatively easy process.
When I need to move BP's by car I put each snake in a individual snake bag (pillow cases work too) and put the bags in a rubbermaid. Everyone should have a floor space and no one should be on top of another snake (most likely not going to be a problem for you).
Finally I like to take a thermometer (doesn't have to be anything expensive, a regular Petco one works fine) and place the probe inside the rubbermaid to maintain an idea of the temp is inside.
The #1 killer of Ball Pythons while transporting is heat vents. DO NOT point any vent pumping out heat towards your BP(s). They will overheat quickly (which is lethal). I transport mine at 70-83 degrees (If I see 81+ I crank up the AC).
Remember, being a little cool will not hurt your BP during a trip (they tolerate it during overnight shipping), but overheating can quickly kill your BP.