in addition to the points mentioned in the article I would think that bites from animals with longer fangs i.e. vipers, pitvipers.this cream would not be very useful due to the fact that the venom is not typically delivered to the lymph system. I also would think that slowing down the spread of venom although may potentially save someone’s life may very well cost them a limb due to more time for the venom to cause necrosis. maybe not a big concern for allot of Ozzy hots, but for some like the red bellied black a real point of concern.