Looks like an abscess to me. I had a Borneo Shortail Python that got one of those once, it started with what appeared to be a tooth problem ? Vet thought he might have broke the tooth on impact with a hard part of the rats head (he hit those rats HARD). No knowing , but the abscess started in a tooth region. It looked very similar to your picture.
And yes, Vet needed 100%.
Hope she will be alright. Despite intensive vet treatments and lots of meds and shots, my boy didn't make it. He was the best snake ever, too, and so sweet throughout all of this painful ordeal.
If I was you, I wouldn't wait. If it is an infection with an abscess it will have to be surgically removed. As someone said, they don't have "liquid" puss, its a hard mass that can't be drained...
Good luck with your girl, she is so pretty !
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