I breed my own feeders and feed all of my BPs live. There is no difference in nutritional value though. Can the rat bite your snake? Yes, while being constricted it may if in position to do so. As has already been mentioned, just monitor and have Feeding tongs ready (if you don't have tongs a pencil will work in a pinch) if you see the rat trying to bite. Never leave a live rat in there for any period of time unsupervised. One advantage I like about feeding live, if they do not get eaten, I can just put them back into their tub with the rest of the feeders.