i only handle my girl for 20 minutes at a time and about 2 x's per week. i DO NOT touch her when she's in shed and during the 2 days after a meal.
honestly though IMHO, keeping in mind that balls are by nature very shy and timid creatures it would suffice to say that alot of handling (like every day for example) would only stress them out.
there's a phrase going around and it's "a hiding bp is a happy bp."