X3 I've never fed a large or jumbo rat. They are the ones that pose a significant risk. Any rat or mouse can but I assume your are feeding adult mice? Guess what I had an adult mouse literally go after a juvy baby that I hadn't switched yet. Guess what I killed it 2 seconds after I saw it going after the snake. I feed smaller rats. Usually weanlings or small mediums they are like 8 weeks old at that stage. The mostly have no idea what a snake is and haven't built up their predator awareness. A jumbo adult not to mention is just way to big a meal even for the largest ball, bur they have a much higher sense of predator in the mist plus they are big so when the snake strikes they can do some serious damage before they are completely killed. Just because they can stuff it in their mouths doesn't mean they should.