Frequent, short handling sessions are the way to go. My girl would strike and attempt to tag me if I ever got within range, so I essentially had to start handling her by ONLY touching her, lifting her, etc with my snake hook. She's stopped hissing and striking, and in the past month I've even free-handled her on two occasions.
Even though she's only ~500 grams give or take, she's given me the worst bite I've ever had from a snake. I wouldn't want a 20lb adult giving my arm a go.